Kay-Uwe Wagner Selected Research

Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)

4/2014	Stat5 regulates the phosphatidylinositol 3-kinase/Akt1 pathway during mammary gland development and tumorigenesis.
2/2004	Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten.

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Kay-Uwe Wagner Research Topics

Disease

35	Neoplasms (Cancer) 05/2024 - 05/2002
23	Breast Neoplasms (Breast Cancer) 11/2023 - 05/2002
7	Carcinogenesis 11/2023 - 05/2002
6	Pancreatic Neoplasms (Pancreatic Cancer) 05/2024 - 10/2012
6	Neoplasm Metastasis (Metastasis) 06/2021 - 03/2008
4	Inflammation (Inflammations) 11/2018 - 12/2015
4	Fatty Liver 01/2017 - 04/2011
2	Adenocarcinoma 05/2024 - 10/2012
2	Atherosclerosis 01/2022 - 07/2017
2	Hepatocellular Carcinoma (Hepatoma) 01/2017 - 10/2011
2	Anemia 01/2017 - 02/2013
2	Disease Progression 11/2016 - 12/2015
2	Infections 11/2010 - 11/2004
2	Carcinoma (Carcinomatosis) 12/2008 - 03/2008
1	Primitive Neuroectodermal Tumors (PNET) 10/2021
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 10/2021
1	Retinoblastoma (Glioblastoma, Retinal) 01/2020
1	Hypertrophy 01/2019
1	Cardiomegaly (Heart Hypertrophy) 01/2019
1	Rare Diseases (Rare Disease) 01/2018
1	Adenoid Cystic Carcinoma (Cylindroma) 01/2018
1	Chronic Disease (Chronic Diseases) 01/2017
1	Fibrosis (Cirrhosis) 01/2017
1	Ascites 01/2017
1	Varicose Veins (Varicose Vein) 01/2017
1	Portal Hypertension 01/2017
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2017

Drug/Important Bio-Agent (IBA)

11	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2004
6	CytokinesIBA 05/2024 - 11/2010
6	LigandsIBA 05/2024 - 05/2002
6	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 05/2024 - 09/2007
6	Phenobarbital (Luminal)FDA Link 11/2023 - 03/2014
4	Janus Kinase 2IBA 01/2022 - 08/2009
4	Tsg101 proteinIBA 02/2020 - 11/2002
4	Janus KinasesIBA 11/2018 - 01/2011
4	Growth Hormone (Somatotropin)IBA 07/2017 - 04/2011
4	STAT5 Transcription FactorIBA 10/2016 - 05/2002
3	Janus Kinase 1IBA 05/2024 - 01/2017
3	Messenger RNA (mRNA)IBA 01/2022 - 05/2015
3	CarcinogensIBA 01/2021 - 05/2002
3	Oncogene Proteins (Oncogene Protein)IBA 02/2020 - 01/2012
3	Small Interfering RNA (siRNA)IBA 01/2019 - 05/2013
3	Angiotensin IIIBA 01/2017 - 06/2011
3	Phosphotransferases (Kinase)IBA 12/2016 - 01/2011
3	Tyrosine (L-Tyrosine)FDA Link 11/2016 - 09/2007
3	Cyclin D1IBA 01/2014 - 08/2009
3	CyclinsIBA 01/2014 - 08/2009
2	ClaudinsIBA 11/2023 - 01/2021
2	ruxolitinibIBA 01/2022 - 02/2013
2	Estrogen ReceptorsIBA 09/2021 - 12/2019
2	Insulin-Like Growth Factor I (IGF-1)IBA 01/2019 - 07/2017
2	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 01/2019 - 02/2004
2	Endosomal Sorting Complexes Required for TransportIBA 01/2019 - 11/2016
2	Erythropoietin FDA Link 01/2017 - 02/2013
2	IronIBA 01/2017 - 06/2011
2	MucinsIBA 12/2015 - 10/2012
2	Hormones (Hormone)IBA 04/2014 - 08/2013
2	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 04/2014 - 02/2004
2	Cyclin D3IBA 01/2014 - 12/2011
2	LipidsIBA 08/2013 - 02/2004
2	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2011 - 07/2011
1	Interleukin-6 (Interleukin 6)IBA 05/2024
1	Apolipoproteins E (ApoE)IBA 01/2022
1	RNA (Ribonucleic Acid)IBA 01/2022
1	Glucose (Dextrose)FDA LinkGeneric 01/2022
1	CholesterolIBA 01/2022
1	Liver X ReceptorsIBA 01/2022
1	Tamoxifen FDA LinkGeneric 10/2021
1	Cre recombinaseIBA 10/2021
1	Recombinases (Recombinase)IBA 10/2021
1	Everolimus FDA Link 10/2021
1	Mechanistic Target of Rapamycin Complex 2IBA 10/2021
1	EnzymesIBA 10/2021
1	NAD (NADH)IBA 10/2021
1	Niacinamide (Nicotinamide)FDA LinkGeneric 10/2021
1	TransferasesIBA 10/2021
1	KPT-9274IBA 10/2021
1	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 10/2021
1	CateninsIBA 10/2021
1	p21-Activated KinasesIBA 10/2021
1	Estrogens (Estrogen)FDA Link 09/2021
1	ProlactinIBA 09/2021
1	Biomarkers (Surrogate Marker)IBA 06/2021
1	MicroRNAs (MicroRNA)IBA 06/2021
1	Pertussis ToxinIBA 01/2021
1	Progesterone Receptors (Progesterone Receptor)IBA 12/2019
1	Monensin (Coban)IBA 01/2019
1	IGF Type 1 Receptor (IGF 1 Receptor)IBA 01/2019
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 11/2018
1	Methionine (L-Methionine)FDA Link 01/2017
1	HepcidinsIBA 01/2017
1	Rho Guanine Nucleotide Exchange FactorsIBA 01/2017
1	Carbon Tetrachloride (Tetrachloromethane)IBA 01/2017
1	Choline (Choline Chloride)IBA 01/2017

Therapy/Procedure

13	Therapeutics 04/2023 - 08/2009
3	Drug Therapy (Chemotherapy) 10/2021 - 11/2004
1	Precision Medicine 09/2021
1	Heterologous Transplantation (Xenotransplantation) 01/2021
1	Microspheres (Microsphere) 01/2017
1	Erythrocyte Transfusion 01/2017